If you have surgery coming up, this one's for you.

On Nov 5, Orthopedics Today ran a commentary telling surgeons to ask every patient about peptides by name. Not "any supplements?" By name.

Bar chart: new patients with documented BPC-157 use went from 4 in early 2020 to 134 in early 2026.

Documented BPC-157 use in US medical records. AJMC, Oct 29 2026. Preprint, not peer reviewed.

What they're being told to write down:

  • The compound

  • Where you got it

  • Your dose

  • How you take it

  • How long you've been on it

The same piece tells them to have you stop unregulated injectables before elective surgery.

Then comes the line that matters. No data define a safe hold period.

Nobody has studied how long you should stop. Not two weeks, not a month. There's no number because no one has run it.

Why they're suddenly asking. A group searched more than 15 million medical records and found 1,039 people with documented BPC-157 use. New users went from 4 in early 2020 to 134 in early 2026. Pain was the reason for a third of them. It's a preprint and it hasn't been peer reviewed yet, and the guy who ran it says the real number is higher because most doctors never ask.

Here's my take.

The honest move is to tell your surgeon. Not because the peptide is the problem, but because the guessing is. If something goes sideways during a procedure and nobody knew what you were on, you've handed them a mystery to solve while you're on the table.

And you're going to get a doctor who's never heard of half of what you're running. Tell him anyway. Write it down, hand it over, let him look it up.

The old advice was keep it to yourself because they'll judge you. That advice was fine when nobody was asking. They're asking now.

Have you ever told a doctor what you're actually taking? Hit reply, I want to know how it went.

Keith